What is aplastic anemia ?Symptoms Treatment

Nowadays, there are many factors that can greatly harm the health.Aplastic anemia - a disease associated with profound myelosuppression, especially young hematopoietic cells.This hyperchromic anemia at which the amount of hemoglobin and red blood cells is reduced, and hematocrit increased.

Due to incorrect synthesis of almost all cells of the hematopoietic system, will be observed very severe disorders of all organs.

Etiology and pathogenesis

The causes of this disease, can be both endogenous and exogenous.Among the endogenous factors play a dominant role - genetic mutation encoding the synthesis of cell in the bone marrow.Such diseases include familial aplastic anemia (Fanconi) and aplastic anemia (Ehrlich).

Fanconi Anemia is characterized by severe anemia, where the bone marrow is completely lost the ability to regenerate any number of blood cells.In case of complete emptying of bone marrow say panmieloftize.Anemia Ehrlich has a progressive course and is characterized by a complete loss of th

e bone marrow.Clinically it can manifest bleeding or sepsis accession.

Exogenous factors include:

  • ionizing radiation (radiation anemia);
  • effects of toxic substances (benzene, heavy metals, etc., toxic anemia.);
  • effects of drugs (eg cytostatics, drug anemia);
  • anemia infectious nature;
  • autoimmune anemia.

Symptoms of aplastic anemia

By type of anemia can be acute, subacute and chronic.

fulminant, which is rare, can not be stopped by any treatments.Therefore, usually the outcome of such a form is the death of the patient.

However, often seen chronic anemia, in which the patient seeks help in the progressive stages of pancytopenia.

The main complaints of the patient include: First, weakness, dizziness, headaches, fatigue, ie,all the usual signs of anemia (anemia syndrome).This is due to the fact that the synthesis of erythrocytes broken, and thus there is no normal oxygen transport and hypoxia.

Secondly, due to violations of platelet synthesis observed increased bleeding, because even with minor injuries may not stop bleeding.The skin will be visible petechiae, ecchymosis, bruising, and will experience bleeding gums and uterine bleeding (hemorrhagic syndrome).



And thirdly, already at an advanced stage because of reduced synthesis of a number of immune cells may be complicated by infections or even sepsis join.

Effective treatment for aplastic anemia

The most important criteria of the treatment is to correct the failure on the part of the blood and symptomatic therapy.How to treat anemia solves only a doctor, because each person needs an individual approach.

In Fanconi anemia only cure is a bone marrow transplant, but if this is not possible, use a therapy with aplastic anemia of exogenous origin: red blood cell transfusions and platelet prescribe suppressive therapy, and antibiotic therapy is required when joining the infection.At strongly expressed hemorrhagic syndrome spend hemostatic therapy.

How to cure anemia is you depends not only on the treatment but also on you.So you just need to know that you need to have a case of anemia, medication because medication does not always help you in treating diseases.

However, there is no specific menu for anemia.The doctor advises to eat more food containing sufficient quantities of proteins, especially of animals, it promotes the synthesis of hemoglobin and red blood cells.Restrict your diet in fats that inhibit hematopoiesis, and to use products containing in its composition of iron, cobalt, manganese, and zinc (liver, eggs, cereals, vegetables, fruits, yeast, fungi, etc.).

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