Normal blood protein in the adult is of 45 to 85 grams / liter.And this is a very important indicator for determining the number of serious abnormalities in the body, so its correct definition is of interest to the practitioner.
Human blood is made up of the cell, and the liquid portion (plasma).Plasma consists of water and of certain substances - carbohydrates, proteins, anions and cations, as well as molecules of nutrients derived from food, lipid metabolic breakdown products.The proteins constitute about 7% of the liquid portion of blood components.
functional significance of proteins
Fluctuations in protein levels and indicators are crucial as protein fractions have a number of important functions in the body.Total plasma protein level is determined mainly albumin, globulin and fibrinogen, since the other protein components are there in small quantities, and are not the deciding factor for the life of the organism.
Albumin have low molecular weight and are a reserve for the use of the vital orga
Globulins have a higher molecular weight and account for almost half of the blood proteins.Their primary role - to provide immune protection in response to the introduction of foreign substances and pathogens.Synthesized by lymphocytes.
Fibrinogen is involved in the basic processes of blood coagulation.
general properties of protein components of the blood are to ensure and colloidal osmotic pressure.Protein bodies are the basis for constructing all cell and tissue structures of the body.
protein Reduced blood
In which case, however, is determined by low protein in the blood?Hypoproteinemia there is not always due to an illness, it may be accompanied by some special status.
So, kids early age is often a decrease in the total protein indicators.It can be during pregnancy, especially in the last trimester, the mother during breastfeeding, physical activity, sometimes the phenomenon contributes to the long-term lack of exercise (lying in bed in critically ill patients).This is due either to inadequate intake of protein, or the presence of a high demand for it.Sometimes protein decrease was observed due to ingestion of certain drugs (for estrogen replacement therapy).
Drinking excessive amounts of fluid volume increases of plasma due to the water component and is relative hypoproteinemia. The same condition is marked in violation of the liquid excretion by the kidneys, severe heart failure, intravenous solutions.
absolute reduction of protein observed in pathological conditions, when it is disturbed absorption or synthesis during liver disease and digestive organs, or if it is breakdown and excretion (renal disease, bleeding, burns, complex surgery).Reduced
protein leads to the fact that reduced oncotic pressure, and the liquid portion of the blood goes into the tissue, causing the appearance of edema.Thus there is a thickening of the blood, and can occur thrombosis and thromboembolism, leading to the development of heart attacks and strokes.
When a albuminosis?
High blood protein observed much less frequently.This happens when dehydration (fluid loss) during the occurrence of profuse diarrhea and uncontrollable vomiting, peritonitis, and this figure is relative.
protein increase occurs due to excessive synthesis of his pathological fractions with cancer pathology, autoimmune conditions and multiple myeloma.Due to the globulin fraction of this phenomenon occurs in severe infectious process.
While receiving corticosteroids and corticotropin amount of blood protein may also increase.
Increased blood protein can lead to eating disorders tissue as necessary substances worse penetrate into the cells.
Norma proteins in the blood is determined by a special biochemical analysis.It is produced in the morning, on an empty stomach.If there is blood in the fence need more time, then a break between it and the last meal should be at least 8 hours.
absolute protein reduction has the greatest clinical significance.Most often, when hypoproteinemia observed decrease in albumin fraction.Their optimal level indicates normal metabolism and good health, and not enough to talk about the decline of vitality and violation of metabolic reactions.
degree of reduction of this indicator helps to determine for certain diseases, and often is the first sign of trouble in the body associated with impaired protein metabolism.
on effectiveness research can significantly affect food intake (especially a high-fat diet), physical activity, alcohol, drugs, tea, coffee.
- In primary diagnosis of any disease.
- To understand the severity of a pathological condition.
- In order to dynamically control the treatment.
- To check the reserve forces prior to the medical treatment or surgery.
- In human inspection for the purpose of prevention.
should strictly comply with the advice of a doctor preparing for the procedure before the passage of the study, because it can be critical for diagnosis, routine inspection, or check on the effectiveness of the treatment.
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