Lupus : How is the disease and clinical picture

Systemic lupus erythematosus is a representative of systemic connective tissue diseases (systemic connective tissue), in which the body under the influence of autoimmune antibodies produced to its own healthy cells and tissues, inflammation processes run.

This characteristic changes can occur in almost any system of the human body, because the connective tissue is an essential component of every organ.

So far, none of the studies carried out by rheumatologists, could not find the cause, the effect of which on the organism alters the normal response of the immune response, but proved the influence of predisposing factors capable of the combined effect of cause specific problems (the more of these factors, the harder it is fordisease).

In addition, the special status of the human body were found, in which are found the markers that indicate violations of the immune response, but does not develop.Symptoms of SLE in this case can not be detected even with the most careful clinical and instrumental ex

amination of the patient.

Why there is lupus?

In those cases where the patient, the patient often arises systemic lupus erythematosus - causes of the disease can not be identified even by careful examination.

In some cases, patients are found specific antiviral antibodies to Epstein-Barr virus, which allows to attribute the disease to a so-called "slow infections", while all patients with long-term existence of systemic lupus erythematosus in the survey expelled antibodies to virtually all body tissues and individual componentscells.

There is information about the impact of hormonal imbalance on the possibility of developing lupus - the highest incidence is found in adolescent girls at puberty and in women in the waning reproductive system, as well as the presence of a genetic predisposition systemic disease systemic lupus erythematosus is often detected among members of the samefamilies.

This is why women with a predisposition to lupus strongly recommend use of hormonal contraceptives and family planning in the process they are advised not to resort to abortion - a sudden change in hormonal levels can cause the disease itself or cause aggravation.

In answering the question - whether lupus contagious, doctors say long-term studies have proved the impossibility of transmission of this disease as a normal infection.

Epstein-Barr virus, rubella pathogens or other viral infections can only trigger disruptions in the immune system, and triggers antibody active products to the body's own tissues, first of all - to the connective tissue.

That is why the most characteristic lesions in lupus are pathological processes in the skin, musculoskeletal system organs, the heart and major blood vessels, lungs, kidneys, nervous tissue, blood-forming organs.

As the disease spread?

If we talk about how transferred lupus, the disease itself is not covered in the usual for most people, the concept of the word - a person may be disrupted immune response, and any triggers only stimulate excessive production of antibodies to the body's tissues in susceptible patients.

Aggravating factors considered:

  • hormonal changes;
  • abortion;
  • use of certain drugs - drug lupus may independently take place after stopping treatment, provoking the development of immune disorders;
  • excessive solar radiation;
  • vaccination;
  • excessive physical activity and psychological stress.

clinical picture

Depending on the severity of symptoms and the severity of the patient's condition released:

  • acute form of lupus, which are characterized by severe multiple organ lesions of virtually all organs and body systems.

disease begins fever, signs of severe intoxication, the growing symptoms of the respiratory, circulatory, excretory and nervous systems.If not started timely treatment, the disease can cause death of the patient;

  • subacute lupus erythematosus has a milder course and symptoms of multiple organ injury without treatment developed in 2-3 years, but the use of the opportunities of modern medicine allows you to securely monitor the activity of the autoimmune inflammation;
  • chronic form of foreign currency - it is characterized by the fact that develops slowly progressive lupus erythematosus - cutaneous form of the disease, in which in the foreground a specific characteristic of the defeat of the joints and skin.

In case cutaneous lupus erythematosus is not detected in a timely manner, and, accordingly, no measures are being taken, preventing generalization of autoimmune inflammatory process, after a sufficiently long period of time revealed internal organ damage symptoms.

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