How diagnosed and treated hepatitis C in children ?applied methodology

in recent years have increasingly diagnosed hepatitis C in children and adolescents of all ages.Hepatitis C - is an infectious disease affecting the liver.Once in the blood, the virus invades the liver cells and multiply gradually destroys them.In addition, changes in the structure of proteins Sensor detection cells affected the liver and immune system, taking over the alien cells, active struggle begins by producing antibodies.A characteristic feature of the virus is its ability to mutate.To date, at least six known genotypes, each of which has its subtypes.

main causes of hepatitis C in children:

  • infection from the sick mother during childbirth;
  • infection during various medical procedures using non-sterile instruments, as well as during a blood transfusion;
  • use other people's personal hygiene items (razors, manicure tools);
  • piercings, tattoos and the like, made in dubious salons;
  • addiction among teenagers;
  • sexual activity during menstruation.


The disease develops gr

adually, the incubation period lasts from 5 to 12 weeks.The first signs of hepatitis C may even occur 6-12 months after infection.Depending on the clinical picture distinguish typical (accompanied by jaundice) and atypical (anicteric or subclinical form) hepatitis.Depending on the duration of the disease are acute (3 months), prolonged (3 to 6 months) and chronic (over 6 months) hepatitis.

Typically, an acute form of the disease are asymptomatic and in most cases are diagnosed by pure chance.The chronic form of the disease is cyclical, that is, the phase of exacerbation smenivayutsya phases of remission.

are the main symptoms of this disease in children:

  • fatigue, weakness, drowsiness;
  • fever to 37,5-38ºS, chills, aches in the joints;
  • loss of appetite, nausea, vomiting;
  • or foam and dark urine;
  • lightening of stool;
  • discomfort or pain in the right hypochondrium;
  • yellowing of the skin, mucous membranes of the mouth;
  • eyes hepatitis have icteric coloration varying degrees of severity;
  • accumulation of fluid in the abdomen (indicates the development of cirrhosis of the liver).

should be noted that children hepatitis is more severe and rapidly leads to cirrhosis of the liver and other undesirable consequences.

The terrible hepatitis C?Gradually progressive chronic form of the disease can lead to consequences such as cirrhosis and liver cancer, and kidney disease, a thyroid gland.

How to diagnose the disease?

For complete and accurate diagnosis if you suspect the presence of hepatitis C virus is carried out general and biochemical blood tests, coagulation, as well as tests for antibodies to hepatitis C virus and HCV-RNA, which are held by ELISA and PCR.Positive results of both tests is the confirmation of the presence of hepatitis C. Also performed abdominal ultrasound.In some cases, additionally required a liver biopsy.Based on the above research doctor will be able to draw conclusions about the type of disease, the level of its development, the degree of liver damage and naznachiteffektivnoe treatment of hepatitis C, as well as to determine the timing of treatment of hepatitis C, depending on its genotype.

Particular attention should be paid to hepatitis in newborns, since in this case the interpretation of the results of research should be carried out, since some children may have revealed the presence of RNA of hepatitis C at a negative response to an antibody, which may indicate a so-called seronegative chronic hepatitis C. Laboratory tests are carried out immediately after birth, and at the age of 1, 3, 6,12 months.

treatment of hepatitis C in children

hepatitis C treatment should deal with doctor-hepatologist.Every day there is more and more variety of advertising tools and techniques to effectively get rid of this disease.However, doctors warn that there is no miracle pill or medicine from the disease.To date, the only effective method is the use of antiviral drugs interferon-alpha and ribavirin.The treatment regimen for hepatitis C is chosen doctor individually for each patient, taking into account the genotype of the virus and many other factors.For effective treatment, these drugs are usually combined.However, in case of intolerance to a patient one of them, a doctor may decide to designate a single agent.

Antiviral therapy has a number of side effects.Thus, ribavirin in rare cases can cause headache, dyspepsia light, changes in blood (symptoms of hemolytic anemia, increased levels of uric acid).The intolerance to this drug is very rare.

As for interferon, then within a few hours after the first dose in most patients following adverse symptoms appear:

  • fever up to 38-39ºS, aches, chills;
  • muscle pain;
  • fatigue and weakness.

This condition can last from a few hours to 2-3 days.As the body's addiction to the drug the patient feel better.However, weakness and lethargy may be present for a long time.After 2-3 months subject to changes in blood analysis (decrease in white blood cells and platelets).

Furthermore, some patients may experience side effects such as weight loss, hair loss, dry skin.

To facilitate the general condition and accelerate recovery can be assigned to an auxiliary therapy for this virus.It involves taking hepatic (essentseale, Kars, Silibor, Silimar), which have properties that support the liver, sorbents (activated carbon, enterosgel) and immunomodulators.

course of HCV treatment usually lasts from 6 to 12 months.

Since the disease caused by a virus, antibiotics hepatitis (as well as the uncontrolled treatment of folk remedies) do not give a positive effect, but rather harm.

therapy against this disease is contraindicated in the following cases:

  • in the presence of chronic diseases (diabetes, heart failure, obstructive pulmonary disease);
  • people who have had organ transplants;
  • intolerance of any drug against hepatitis C;
  • children under the age of 3 years.

prognosis of hepatitis C is variable.Typically, recovery from the acute form of the disease occurs in about a year.The chronic form may take place over the decades.Hepatitis C in deteyrannego age has a poor prognosis due to the fact that it is impossible to carry out treatment in full.

In no case can not let the disease take its course, or self-medicate.Timely care doctor will not only increase the chances of a favorable outcome, but also help to avoid infecting other family members.

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