Hepatitis C virus - infectious liver disease, which interferes with its function.The disease may be acute or chronic.Upon infection with hepatitis C virus in 80% of cases, a person can not independently cope with it and form an acute becomes chronic C. In 20% of all cases of hepatitis C cure comes alone.
Way infection viral disease
Currently, scientists identified several pathogen genotypes of hepatitis C - a genotype 1 (1a, 1b), 2 (2a, 2b), For.The type of agent depends on the duration of the virus in the human body, as well as the effectiveness of treatment.
Infection occurs in the following ways:
- damage the integrity of the skin and mucous membranes (tattoos, piercing, manicure, pedicure, acupuncture).
- sexual way of infection, in violation of the integrity of the mucous membranes.
- re-use of disposable instruments, syringes and needles.
- use instruments poorly treated when you visit a dentist or gynecologist (examination or manipulation).
- child transmission during childbirth by a sick mother.
- addicts injecting drug use.
path of infection with hepatitis C virus is mainly hematogenous.
Symptoms and signs of the disease
for timely diagnosis and successful treatment it is necessary to know how to manifest hepatitis C. Moreover, the symptoms of this form have their own characteristics.
The incubation period (time from infection until the first signs of the disease) with viral hepatitis C is 20 to 140 days.The peculiarity of this disease is that you never know how many he has seen.It is noted that, in spite of the long incubation period, the manifestation of hepatitis C often occurs in 50-60 days.
Another feature is that the hepatitis C disease, the symptoms are not expressed, and this feature also distinguishes the clinical course of this form of the disease.According to statistics, the majority of infected hepatitis C do not feel sick and do not show the people of the complaint.
Signs of disease in adults are not much different from the symptoms of the disease in children, with the only difference being that the children may not complain.Only observational parents may notice changes in the behavior of the child, the state of appetite and the presence of other, less visible symptoms.
Despite the paucity of clinical hepatitis C, in some cases, an acute form it has the following symptoms:
- Sudden weakness and malaise.
- Dull or aching pain, sometimes appearing in the right upper quadrant.
- Decreased appetite, in rare cases, nausea and vomiting.
- Pain in the joints and muscles.
- disorder chair, which manifests recurring diarrhea.
- Change the color of feces and urine.
- jaundiced color of the skin and sclera.
All of these symptoms appear in this order (on the list).This means that the light cal hepatitis, dark, red-brown urine, and jaundice of the skin symptoms appear after all.
Language hepatitis C may also turn yellow, but in the last turn.Slow development of infections and the lack of severity of symptoms create conditions for the transition of the acute form of chronic.
Based on the clinical picture of acute hepatitis C, distinguish the inactive and the active form of the disease.When an inactive form, even a form of acute symptoms.When the above symptoms are observed active.
When active form can be extrahepatic manifestations of hepatitis C, which are somehow related to hepatitis.It is a disorder or disease in other organs and systems of the body that accompany the course of hepatitis C.
most common extrahepatic manifestations of hepatitis C are on the skin in the form of hemorrhagic petechiae or stars in the form of joint pain.Less common symptoms of the immune, nervous and urinary systems.
Among all diseases secrete Behcet's disease in which there is a canker of the mouth, eyes, genitals.May develop premature graying, cerebral vasculitis and cryoglobulinemia in which cryoglobulins accumulate in the blood.These specific proteins impede blood flow in arteries and veins, causing many problems.
Lesions of the endocrine system is expressed in the appearance of patients with hepatitis C virus type 2 diabetes.It may be a extrahepatic manifestations, like fibromyalgia, which is characterized by muscle pain, chronic fatigue and sleep disturbance.
disease can cause lichen planus, which is characterized by itching, scaling, and hair loss.On the part of the kidney may be membranous nephropathy, manifested by high blood pressure and edema.
It is important to rule out infection of hepatitis C virus with the appearance of unexplained and mysterious symptoms of the organism It is necessary to pass inspection.
diagnosis of hepatitis C is placed on the basis of these markers, biochemical blood tests, data on hepatitis UZI.Krov rented an empty stomach, in specially equipped laboratories.
Among serological techniques used PCR method in which the viral RNA is determined and specific IgM.And, all this can be found both at the time of acute illness, and in the case of suffering, but not diagnosed hepatitis C
The level of liver enzymes ALT and AST in the blood can be seen on the activity of the disease at the time of the study.Recently used elastometry liver, which allows you to determine the degree of fibrosis (connective tissue replacement) without liver biopsy liver tissue.
liver biopsy in hepatitis C today is one of the most reliable tests in lesions of the liver with hepatitis C. It is possible to determine the condition of the liver stage of the disease, to exclude other liver diseases, to choose treatments.Most importantly, the liver biopsy to determine the prognosis of the disease.
procedure taking material is not as complex analysis and is performed under local anesthesia in the doctor's office.Before the procedure, it is recommended not to take medicines, including medicines that may increase the risk of bleeding.
liver biopsy for hepatitis C is performed by percutaneous needle three types - cutting, aspiration and spring.The material for the biopsy is taken long 1 -3 cm and a diameter of 1-2 mm.During the procedure, some patients experience little pain, but generally the procedure is painless.
In today's world it is sometimes difficult to choose the time to get a complete examination.For a quick determination of virus in the blood have a rapid test for hepatitis C.
Express test - a simple and convenient procedure for the rapid determination of the presence of virus in human blood.It is produced in the laboratory and home.After the puncture, blood samples taken finger lancet and the test result is immediately visible on the display.Two strips indicate the presence of virus, one of the bars - the lack of it.