sarcoma - a malignant neoplasm of non-epithelial origin.All sarcomas develop from connective tissue cells (as opposed to cancer that develops from the epithelium cells), and is approximately 15% of all malignant tumors.
This bone sarcoma is rare.Depending on the characteristics of cellular structure, histological structure of bone sarcoma is divided into the following types:
- Ewing's sarcoma
Among young people, children and adolescents the most frequent sarcomaEwing and osteosarcoma of the femur (shin, shoulder, pelvis and elbow bones are affected a little less).Older people are more prone to chondrosarcoma and fibrosarcoma.
Causes of illness
etiology of this disease is not fully understood.Factors contributing to the development of malignant tumors, include the effect of carcinogens, toxic chemicals, radiation, and even viruses.Very often the disease begins to develop after any injury.Although it is believed that
Sometimes bone sarcoma arises with a history of benign bone disease, fibrous dysplasia, Paget's disease.
Because sarcoma of the femur occurs mostly in children and adolescents is one of the reasons for its occurrence is considered intense bone growth.It was found that the disease more susceptible to boys of high growth.
Symptoms and Diagnosis
Unfortunately, the initial stage of the disease is very difficult to diagnose and has no distinct features.Disturb can only dull pain near the lesions mainly at night.As the tumor enhanced pain symptom and can not be removed by conventional painkillers.Near the affected area extended venous network.joint palpation causes a sharp pain.Very quickly grow metastases, sometimes hitting virtually message body.
for early diagnosis of malignant bone tumor is necessary to perform X-rays and a biopsy even if not strong pain and joint swelling.In no event it is impossible to carry out physiotherapy and anti-inflammatory therapy before the diagnosis, as it may contribute to the growth of the tumor.
If malignant neoplasms set, for further study using computed tomography, MRI, intravenous study with contrast.It is important to determine the stage of the disease for a choice of tactics of further treatment.
the following options for the treatment of sarcoma:
- Chemotherapy.Most often used in conjunction with surgery and before the operation is carried out - in order to reduce the volume of the tumor and after - for the destruction of certain malignant cells, prevention of metastases and relapses.
- operation.If previously injured limb amputation was inevitable, now widely used sparing surgery with removal of bone area and the use of metal, plastic or natural implants.The presence of small metastases is eliminated and further chemotherapy is not an obstacle for the operation.
- Radiotherapy.The most often used in case of failure of surgery and chemotherapy.It has less effect compared to chemotherapy, since the sensitivity of cancer cells to bone sarcoma radiation is low.Nevertheless, there are some types of bone sarcoma (e.g. Ewing sarcoma) when radiotherapy - one of the main methods of treatment.
As in most cases of malignant cancer, the probability of a positive outcome increases with timely diagnosis and early treatment.New technologies, including modern chemotherapy and organ operation, you can save the life of up to 80% of patients.