Cryoglobulinemic vasculitis : clinical presentation and treatment of the disease

rapidly progressive and characterized by severe clinical picture, cryoglobulinemic vasculitis requires immediate medical intervention.Given the fact that this complex pathology requires a serious approach to their treatment should be correct, and the patient agrees to comply strictly with all the doctor needs.

Etiology and pathogenesis

cryoglobulinemic vasculitis is a disease characterized by the appearance of specific proteins in the blood - cryoglobulins.When the temperature goes below thirty-seven degrees, they precipitate and dissolve rapidly when heated.The natural consequence of this reaction is the destruction of the walls of capillaries, which takes place against the backdrop of postponing them cryoglobulins.

also happens to produce antibodies against various proteins, infectious pathology, and other antigens in the human body.

In the absence of a pathological reaction, antigen-complexes antitelovye painless "self-destruct."

to antigens at cryoglobulinemic vasculitis should include:

  • bacteria;
  • viruses;
  • hepatitis C virus;
  • proteins that are a part of the hepatitis B virus core C.

This pathology can be as an independent primary and secondary, advanced against the background of a disease.

reasons for concern

Modern doctors distinguish a variety of signs cryoglobulinemic vasculitis.The specific features should include the appearance of pain in the joints, skin rashes, and specific weaknesses.

clinical picture of the disease is manifested


  1. Skin loses its sensitivity.
  2. specific rash (purple) appears on the lower extremities of the skin.
  3. After the disappearance of lesions formed brown spots.
  4. are formed sores (rare).

Rare manifestations

Essential cryoglobulinemic vasculitis characterized by the appearance of ulcers that occur in the background tissue death.In some cases, there are signs of impaired circulation fingertips upper extremities.The so-called Raynaud's syndrome is dangerous tissue necrosis and gangrene.

also non-specific, rare symptoms should include:

  1. Motor pathology.
  2. paralysis.
  3. Speech Pathology.

Features pain

painful syndrome localized in small and in large joints.The following joints are "at riskĀ»:

  1. shin-tion.
  2. Knee-st.
  3. Beder minutes.

In case of hypothermia painful syndrome increases.Sometimes on this background develop arthritis.

What's the danger?

Essential cryoglobulinemic vasculitis dangerous lesions of vital organs.Under the blow fall:

  • light (sometimes there is a dry cough, shortness of breath);
  • spleen (increased in size);
  • liver (increase in size);
  • kidney
  • (art.davlenie increased blood and urinary protein appears);
  • gastrointestinal tract.

Identifies enemy

cryoglobulinemic vasculitis involves timely medical intervention.Specialist performs the following manipulations:

  • inspection;
  • histological examinations;
  • testing blood for the presence of hepatitis C;
  • ultrasound;
  • radiography;
  • MRI;
  • CT.

Professional help

pathology Treatment has two objectives - blood cleansing and inflammation relief.To achieve the first goal of the patient is assigned to a plasmapheresis and inflammation docked glucocorticoid hormones.

If the disease is very difficult, the doctor makes the decision regarding the appointment of the oppressing immunity cytostatics.

Antiviral drugs are prescribed to the patient in case of hepatitis C.

Unfortunately, a full recovery from vasculitis cryoglobulinemic impossible.But, by following the recommendations of the doctor, the patient receives a guarantee that relapses and worsening excluded.

Like this?Share with friends and acquaintances: